Postdoctoral Researcher
The Welch Laboratory at the University of Michigan is seeking a postdoctoral researcher to develop and apply algorithms, machine learning methods, and statistical models for analysis of single-cell genomic data. Our research focuses on enabling biological discovery by applying novel computational approaches to genomic data. Broadly, we seek to understand what genes define the complement of cell types and cell states within healthy tissue, how cells differentiate to their final fates, and how dysregulation of genes within specific cell types contributes to human disease. The lab publishes in high-impact journals, including Cell, Nature, and Nature Biotechnology.
This postdoctoral position will focus on methods for analyzing and integrating single-cell RNA-seq, single-cell epigenome data, and spatial transcriptomic data as part of several NIH-funded projects. We have data and biological collaborators from several different systems, including mouse bone, mouse brain, and human hematopoietic stem cells. This is such an exciting and fast-moving field that Nature Methods recently selected “Single-Cell Multimodal Omics Analysis” as the Method of the Year 2019 and “Spatially Resolved Transcriptomics” as the Method of the Year 2020.
A unique benefit of this position is the rich set of collaborative opportunities available, allowing truly interdisciplinary training. Our collaborative network includes bench scientists and computational method development colleagues within the Single-Cell Spatial Analysis Program, the Michigan Neuroscience Institute, and the Michigan Institute for Data Science (MIDAS). Additional opportunities for collaboration are available with faculty in the Artificial Intelligence Laboratory in the Department of Computer Science and Engineering.
Desired Qualifications: The ideal candidate will have a PhD in computational biology, bioinformatics, computer science, statistics, mathematics, physics, or related field, and familiarity with high-throughput sequencing data. Life scientists with significant computational expertise should also apply. Additional desirable qualities include the ability to effectively work both independently and in a team, good communication skills, and a love for both computational method development and biological discovery.
Interested applicants should submit a brief statement of interest, CV, and contact information for three references. For questions regarding the position, please contact Dr. Joshua Welch at welchjd@umich.edu. Click here to apply: https://careers.umich.edu/job_detail/212162/research-fellow
Bioinformatician
The Welch Lab at The University of Michigan is seeking a Bioinformatician-Computational Biologist Associate to analyze big datasets, primarily using Welch lab software tools. This includes genetic, epigenomic, transcriptome, single-cell, and population data. The Bioinformatician will also disseminate findings by writing manuscripts for peer reviewed publication and presenting findings at national meetings. The Bioinformatician will also help write proposal applications and perform critical review of scientific literature. There will also be opportunities to train Ph.D., masters and undergradate students, as well as postdoctoral fellows, in data analysis techniques. Master's degree in bioinformatics, computational biology, computer science, or related field; experience with high-throughput sequencing data analysis; and strong coding abilities on R and Python are required qualifications. Click here to apply: https://careers.umich.edu/job_detail/211775/bioinfo-comput-biologist-assoc
Software Engineer
The Welch Lab at the University of Michigan is seeking a software engineer (official title: Applications Systems Analyst Programmer Intermediate). Under general supervision, the programmer will formulate and define system scope and objectives through research and fact-finding to develop or modify moderately complex information systems. He or she will also prepare detailed specifications from which programs will be written, then design, code, test, debug, document, and maintain those programs. The programmer will be competent to work on most phases of applications systems analysis and programming activities. The candidate will typically analyze, compare and evaluate various courses of action and have the authority to make independent decisions on matters of significance, free from immediate direction, within the scope of their responsibilities. The candidate will be responsible for maintaining and extending the LIGER R and Python packages developed by the Welch lab. Other responsibilities will include maintaining and extending Welch lab Python packages for RNA velocity estimation and developing new software tools. Master's degree in computer science or related field and strong coding abilities in C++, R, and Python are required qualifications. Click here to apply: https://careers.umich.edu/job_detail/211777/app-sys-analystprgm-inter